A STEREOLOGICAL STUDY OF CHANGES INDUCED IN SYNAPTIC VESICLES POOLS BY ACUTE STRESS AND THERAPEUTIC DRUGS

Validating ADAM10 as therapeutic target for dementia

The role of lipid synthesis in neuroprotection from diabetic neuropathy

Unrevealing mechanisms of gabaergic control of neuro-schwann cell interaction in peripheral neuropathies

Selective autophagic response to proteotoxicity in motorneurons and muscle of motor neuron diseases

Development of innovative tools for Alzheimer Disease therapy

Cotratto di collaborazione per la realizzazione dell'attività di ricerca avente per oggetto: Psychopharmacology and molecular psychiatry in order to carry out, among other activities, microarray analyses on human RNA samples from depressed patients and cellular neurones

Dissecting the role of CHD7 and SEMA3A signalling in the control of reproduction and alfaction, which are defective in CHARGE syndrome patients

Bioinformatics and cell reprogramming to develop an in vitro platform to discover new drugs for progressive multiple sclerosis (BRAVEinMS)

Bioinformatics and cell reprogramming to develop an in vitro platform to discover new drugs for progressive multiple sclerosis (BRAVEinMS)

Linking PCSK9 to beta-cell physiology and glucose metabolism

The involvement of the small heat shock protein HSPB8 in amyotrophic lateral sclerosis

Understanding allergen potency: role of protein kinase C activation in the vigor of dedritic cell activation - CAAT (rinnovo 3°anno)

Investigating the role of lysosomal acid lipase in immune cells function

Unveiling the impact of ASGR1 deficiency on the immunoinflammatory signature during atherogenesis (ASGR1 )

PCSK9 and cardiac function: bridging cellular lipid metabolism to mitochondrial function and heart failure (PCSK9)

Investigation on the possible role of micrornas in the regulation of chemical allergen potency

Defining the genetic interaction between CHD7 and semaphorin signalling by exploring C.Elegans as animal model

Exploring the Impact of Nanoplastics on Sexual Reproduction by Applying Tailored In Vitro Models of Developing and Maturing GnRH Neurons

Unveiling beneficial effects of a peanut butter meal on postprandial neutrophils activation and endothelial dysfunction in pre-clinical cardiovascular disease

Unveiling regenerative and metabolic features of SBMA muscle cells to identify new therapeutic targets

Unveiling neuroplastic mechanisms in a periphery-to- brain crosstalk in an experimental model of anorexia nervosa

Targeting epigenetic REPROGRamming of innate immune cells in Atherosclerosis Management and other chronic inflammatory diseases

Synaptic Dysfunction in Alzheimer Disease

An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries (Train2Target)

Targeting RAN translation in ALS (Target-RAN)

Membrane-less organelle pathology in ALS: identification of causes and rescuing factors (MLOMALS)

Exploiting regulatory T-cell metabolic reprogramming and vascular tropism for Familial Hypercholesterolaemia immunotherapy

Novel pharmacological approaches to increase ketone bodies availability in Glut1 deficiency syndrome

Basi molecolari per lo sviluppo di strategie chemiopreventive e terapeutiche innovative nel melanoma: recettore estrogenico beta, epigenetica e tocotrienoli

Motor neuron degeneration in Spinal and Bulbar Muscular Atrophy: molecular approaches to counteract mutant androgen receptor neurotoxicity

Translating molecular pathology into a therapeutic strategy in SCA38, a newly identified form of spinocerebellar ataxia

Renal disease in genetic LCAT deficiency: from pathogenesis to therapy

Patent development of new modulators of GPR17, a key receptor in remyelinating processes

Developmental exposure to cocaine as a risk factor for adolescent depression: unraveling the underlying molecular mechanisms in preclinical models

Strategie rimielinizzanti innovative per la sclerosi multipla: focus su GRP17, nuovo recettore coinvolto nel differenziamento oligodendrocitario

Strategie rimielinizzanti innovative per la sclerosi multipla: focus su GPR17, nuovo recettore coinvolto nel differenziamento oligodendrocitario

Patent development of the new modulators of GPR17, a key receptor in remyelinating processes

Naturally gluten free pigmented cereals to modulate the inflammatory status in CD

Patent development of new modulators of GPR17, a key receptor in remyelinating processes