∧ ∨ Type | ∧ ∨ Title | Principal Investigators | Status | ∧ ∨ Year |
---|---|---|---|---|
PRIN2022 - PRIN bando 2022 |
Dissecting the pharmacological mechanisms underlying the therapeutic potential of phytocannabinoids in autism
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
The role of TRPM8 and its dietary ligands in intestinal fibrosis: a translational exploration
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
DEVELOPMENTAL ROLE OF THE MUTANT ANDROGEN RECEPTOR CAUSATIVE OF SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA)
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
STRESS AND PSYCHOPATHOLOGIC DOMAINS: FROM MOLECULAR MECHANISMS TO BRAIN CIRCUITS
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Supporting medication adherence by the Elderly: development of an action framework for different healthcare settings
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Evaluation of Castanea sativa by-products as a source of bioactive molecules against Helicobacter pylori-induced inflammation: a novel sustainable strategy Acronym: CastACTIVE
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Adoptive cell transfer of metabolic reprogrammed T regulatory cells to control atherosclerosis progression and to prevent end organ damage in cardiovascular disease.
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Pharmacological inhibition and genetic deletion of PCSK9: in vitro and in vivo studies on smooth muscle cell aortic calcification
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Stress granules as possible mediators of cardiac damage by dysfunctional HDL in acute coronary syndrome: towards novel pharmacological targets
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Decoding distinctive features of EXtracellular vesicles In TDP-43 proteinopathies - EXIT
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Endometriosis and related pain: novel pathogenetic targets for non-hormonal drugs
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Characterization of pharmacological approaches to counteract the neuropathological, morphological and behavioral alterations induced by anti-GluA3 IgG in Frontotemporal Dementia
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Early social adversity and risk for psychiatric disorders: shedding light on the therapeutic potential of psilocybin
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
The crosstalk between brain and periphery in maladaptive feeding behaviors: Role of the transcriptional repressors histone deacetylases and their therapeutic opportunities
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Attenuating the stress of the endoplasmic reticulum as a strategy to cure the multi-minicore disease
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Targeting hepatitis B virus with PROTAC capsid degraders (TarPaB)
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Immunoregulatory paths of metabolic disease: unveil molecular mechanisms of impaired immuno-vascular response to target visceral inflammation by rewiring regulatory T cell energetic circuits
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
EXTRAcellular Vesicles to Unravel Heart Failure Molecular and Clinical Phenotypes (EXTRAHF)
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
An integrated human-in vitro approach to explore the role of miRNAs in the allergic asthma
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Exploring the role of SEMA6A in the formation of hypothalamic and cerebellar circuits to unravel new molecular mechanisms underlying reproductive and feeding behaviours.
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
PAtient Lipidome As biomarker of Cancer immunothErapy (PALACE study)
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
SLC15A4 (Solute Carrier 15 member A4): integrated in vitro-in vivo analysis and functional characterization
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
Organic cation transporters relevant to drug discovery: multifaceted approaches to unravel their structure/function relationships with the aim of identifying novel substrates and inhibitors enabling their application in therapy
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Ongoing | 2023 |
PRIN2022 - PRIN bando 2022 |
The cellular function of SERINC proteins and their role in retroviral infection.
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Ongoing | 2023 |
PRIN2020 - PRIN bando 2020 |
RE-Plast: targeting functional and structural plasticity in Alzheimer disease. From diagnosis to treatment
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Ongoing | 2022 |
PRIN2020 - PRIN bando 2020 |
New interventional approaches on multiple inflammatory pathways involved in regeneration after trauma and aging- associated diseases
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Ongoing | 2022 |
PRIN2020 - PRIN bando 2020 |
Role of TDP-43 self-assembly in health and disEase: molecular characteristics, cellular Aspects and animal Models
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Ongoing | 2022 |
PRIN2020 - PRIN bando 2020 |
Escaping the ESKAPEs: integrated pipelines for new antibacterial drugs
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Ongoing | 2022 |
PRIN2017 - PRIN bando 2017 |
Integrating metabolism and immunity: cellular and molecular pathways leading to metabolic dysregulation and autoimmunity
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Early life stress and psychopathology: unraveling the mechanisms of vulnerability and resilience
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Multi-center Translational Trial of Remote Ischemic Conditioning in Acute Ischemic Stroke (TRICS). A collaborative study from the Italian Stroke Organization (ISO) Basic Science network
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
The interplay between the “rna/protein quality control system” and “exosomes” as a spreading mechanism in amyotrophic lateral sclerosis (EX_ALS)
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Identification and validation of COmmon pathways at the CrOssrOads of neurodegeneration and Neuroprotection (COCOON)
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Early life social experiences and dysregulation of the brain reward system: The role of endocannabinoid transmission
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
tArGeting brAIn cholesterol traNSporT in Alzheimer’s Disease (AGAINST-AD)
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Low density lipoprotein receptor (LDLR)-independent effects of proprotein convertase subtilisin/kexin type 9 (PCSK9): role in modulating insulin-resistance, ectopic fat accumulation and low-grade inflammation
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Pathogenesis of Chemotherapy-Induced Peripheral Neurotoxicity (Pa-CIPN)
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Role of alpha-synuclein and LRRK2 in Levodopa-induced dyskinesia
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Drug repurposing as a novel strategy to discover pro-regenerative therapies for neurological diseases: the challenge of progressive multiple sclerosis
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Closed | 2019 |
PRIN2017 - PRIN bando 2017 |
Study of the crosstalk between multiple pathways in the regulation of inflammatory processes in models of chronic and degenerative diseases
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Closed | 2019 |