tArGeting brAIn cholesterol traNSporT in Alzheimer’s Disease (AGAINST-AD)

Low density lipoprotein receptor (LDLR)-independent effects of proprotein convertase subtilisin/kexin type 9 (PCSK9): role in modulating insulin-resistance, ectopic fat accumulation and low-grade inflammation

Study of the crosstalk between multiple pathways in the regulation of inflammatory processes in models of chronic and degenerative diseases

Pathogenesis of Chemotherapy-Induced Peripheral Neurotoxicity (Pa-CIPN)

Role of alpha-synuclein and LRRK2 in Levodopa-induced dyskinesia

Drug repurposing as a novel strategy to discover pro-regenerative therapies for neurological diseases: the challenge of progressive multiple sclerosis

Identification and validation of COmmon pathways at the CrOssrOads of neurodegeneration and Neuroprotection (COCOON)

Molecular pathways in Schwannomatosis: exploiting in vitro models for the identification of new therapeutic targets

Early life social experiences and dysregulation of the brain reward system: The role of endocannabinoid transmission

Integrating metabolism and immunity: cellular and molecular pathways leading to metabolic dysregulation and autoimmunity

The interplay between the “rna/protein quality control system” and “exosomes” as a spreading mechanism in amyotrophic lateral sclerosis (EX_ALS)

Early life stress and psychopathology: unraveling the mechanisms of vulnerability and resilience

Multi-center Translational Trial of Remote Ischemic Conditioning in Acute Ischemic Stroke (TRICS). A collaborative study from the Italian Stroke Organization (ISO) Basic Science network

Neuroimmunoinfiammazione nel dolore cronico e in un modello transgenico di Alzheimer: alterazioni sensoriali e cognitivo-comportamentali e nuove prospettive terapeutiche

From mother to child health flow: the impact of the endocrine disruptor chemical Bisphenol A (BPA)

Useful experimental models for dissecting the molecular links between cancer development/progression and the obesity epidemic

Risposte maladattative dello stress: studio dei meccanismi che le regolano per identificare nuovi bersagli terapeutici nelle malattie neuropsichiatriche.

Towards multi-stage drugs to fight poverty related and neglected parasitic diseases: synthetic and natural compounds directed against Leishmania, Plasmodium and Schistosoma life stages and assessment of their mechanisms of action.

Targeting early synaptic dysfunctions induced by alpha-synuclein as a novel therapeutic approach in Parkinson's disease

Meccanismi di patogenesi negli stadi precoci della malattia di Alzheimer: identificazione di target armacologici e biomarkers