Adoptive cell transfer of metabolic reprogrammed T regulatory cells to control atherosclerosis progression and to prevent end organ damage in cardiovascular disease.

An integrated human-in vitro approach to explore the role of miRNAs in the allergic asthma

Assegnazione Dipartimenti di Eccellenza 2023-2027 - Dipartimento di SCIENZE FARMACOLOGICHE E BIOMOLECOLARI

Attenuating the stress of the endoplasmic reticulum as a strategy to cure the multi-minicore disease

Breaking the barrier -An integrated multidisciplinary approach to killGram-negative bacteria through existing antibiotics by making their outer membrane permeable (BREAKthrough)

Characterization of pharmacological approaches to counteract the neuropathological, morphological and behavioral alterations induced by anti-GluA3 IgG in Frontotemporal Dementia

Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy (CardioSCOPE)

Connecting craniofacial malformations with neural crest splicing defects by defining the role of nuclear cyclophilin NKTR (GMR22T1054)

DEVELOPMENTAL ROLE OF THE MUTANT ANDROGEN RECEPTOR CAUSATIVE OF SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA)

Decoding distinctive features of EXtracellular vesicles In TDP-43 proteinopathies - EXIT

Dissecting the pharmacological mechanisms underlying the therapeutic potential of phytocannabinoids in autism

Dissecting the role of anti-GluA3 antibodies in Frontotemporal Dementia: from bench to bedside

EXTRAcellular Vesicles to Unravel Heart Failure Molecular and Clinical Phenotypes (EXTRAHF)

Early social adversity and risk for psychiatric disorders: shedding light on the therapeutic potential of psilocybin

Endometriosis and related pain: novel pathogenetic targets for non-hormonal drugs

Escaping the ESKAPEs: integrated pipelines for new antibacterial drugs

Evaluation of Castanea sativa by-products as a source of bioactive molecules against Helicobacter pylori-induced inflammation: a novel sustainable strategy Acronym: CastACTIVE

Exploring the role of SEMA6A in the formation of hypothalamic and cerebellar circuits to unravel new molecular mechanisms underlying reproductive and feeding behaviours.

FuEl ThE bRaiN In healtThY aging and agE-relateD diseases (ETERNITY)

INNOVATIVE STRATEGIES FOR DEPRESSION TREATMENT: NOVEL PHARMACOLOGICAL TARGETS AND PRECLINICAL STUDIES FOR THE PERSONALIZATION OF THERAPY

Identifying Disease signatures of degenerative dementias: a focus on autoimmunity and inflammation

Immunoregulatory paths of metabolic disease: unveil molecular mechanisms of impaired immuno-vascular response to target visceral inflammation by rewiring regulatory T cell energetic circuits

Improving diagnosis and therapy for familial dyslipidaemias: a network of general practitioners and specialised lipid centers

Investigating the neuro-immune-metabolic interfaces in human and experimental atherosclerosis

Linking inflammation to progression of neurodegeneration in Parkinson’s disease (LINKING PARK)

Metal-containing Radical Enzymes (MetRaZymes)

Molecular mechanisms of NLRP3-inflammasome inhibition by Leishmania infantum-derived factors in the neuropathogenesis of Alzheimer's disease

NEuroendocrine-metabolic-inflammatory and infection-proneness Profile Testing before and after long-term UNderwater and Extraterrestrial missions (NEPTUNE ISS-PP)

NEuroendocrine-metabolic-inflammatory and infection-proneness Profile Testing before, during and after short-term UNderwater and Extraterrestrial missions (NEPTUNE ISS-SDM)

National Center for Gene Therapy and Drugs based on RNA Technology

New interventional approaches on multiple inflammatory pathways involved in regeneration after trauma and aging- associated diseases

Next generation advanced RNA inhibition therapy to treat cardiometabolic disease (LiverTarget)

One Health Basic and Translational Research Actions addressing Unmet Need on Emerging Infectious Diseases (INF-ACT)

Optimizing Management of Comorbid NASH through a Multidisciplinary Integration and Artificial Intelligence Alliance (OPTIMA-NASH)

Organic cation transporters relevant to drug discovery: multifaceted approaches to unravel their structure/function relationships with the aim of identifying novel substrates and inhibitors enabling their application in therapy

PAtient Lipidome As biomarker of Cancer immunothErapy (PALACE study)

Partnership for the Assessment of Risks from Chemicals (PARC)

Pharmacological block of the prokineticin system and of microglia activation to treat pain and mood disorders in Fabry-Anderson disease

Pharmacological inhibition and genetic deletion of PCSK9: in vitro and in vivo studies on smooth muscle cell aortic calcification

Phase III trial of dopaminergic therapy with rotigotine in patients with mild Alzheimer's disease (DOPAD3)