Valutazione della funzionalità mitocondriale nelle sindromi da Long COVID-19

Molecular mechanisms of NLRP3-inflammasome inhibition by Leishmania infantum-derived factors in the neuropathogenesis of Alzheimer's disease

Valutazione dell’impatto della somministrazione di una statina (atorvastatina) e dell’acido bempedoico sull’attività mitocondriale del muscolo scheletrico

Assegnazione Dipartimenti di Eccellenza 2023-2027 - Dipartimento di SCIENZE FARMACOLOGICHE E BIOMOLECOLARI

Connecting craniofacial malformations with neural crest splicing defects by defining the role of nuclear cyclophilin NKTR (GMR22T1054)

Linking inflammation to progression of neurodegeneration in Parkinson’s disease (LINKING PARK)

FuEl ThE bRaiN In healtThY aging and agE-relateD diseases (ETERNITY)

Breaking the barrier -An integrated multidisciplinary approach to killGram-negative bacteria through existing antibiotics by making their outer membrane permeable (BREAKthrough)

Comprehensive and personalized assessment of acute coronary syndrome by multiomic approach and artificial intelligence strategy (CardioSCOPE)

The involvement of the small heat shock protein HSPB8 in amyotrophic lateral sclerosis (2° annualità)

Toward a green toxicology: new approach methodologies to screen chemical-induced immunotoxicity (GREENTOX)

Dissecting the pharmacological mechanisms underlying the therapeutic potential of phytocannabinoids in autism

The role of TRPM8 and its dietary ligands in intestinal fibrosis: a translational exploration

DEVELOPMENTAL ROLE OF THE MUTANT ANDROGEN RECEPTOR CAUSATIVE OF SPINAL AND BULBAR MUSCULAR ATROPHY (SBMA)

STRESS AND PSYCHOPATHOLOGIC DOMAINS: FROM MOLECULAR MECHANISMS TO BRAIN CIRCUITS

Supporting medication adherence by the Elderly: development of an action framework for different healthcare settings

Evaluation of Castanea sativa by-products as a source of bioactive molecules against Helicobacter pylori-induced inflammation: a novel sustainable strategy Acronym: CastACTIVE

Adoptive cell transfer of metabolic reprogrammed T regulatory cells to control atherosclerosis progression and to prevent end organ damage in cardiovascular disease.

Pharmacological inhibition and genetic deletion of PCSK9: in vitro and in vivo studies on smooth muscle cell aortic calcification

Stress granules as possible mediators of cardiac damage by dysfunctional HDL in acute coronary syndrome: towards novel pharmacological targets

Decoding distinctive features of EXtracellular vesicles In TDP-43 proteinopathies - EXIT

Endometriosis and related pain: novel pathogenetic targets for non-hormonal drugs

Characterization of pharmacological approaches to counteract the neuropathological, morphological and behavioral alterations induced by anti-GluA3 IgG in Frontotemporal Dementia

Early social adversity and risk for psychiatric disorders: shedding light on the therapeutic potential of psilocybin

The crosstalk between brain and periphery in maladaptive feeding behaviors: Role of the transcriptional repressors histone deacetylases and their therapeutic opportunities

Attenuating the stress of the endoplasmic reticulum as a strategy to cure the multi-minicore disease

Targeting hepatitis B virus with PROTAC capsid degraders (TarPaB)

Immunoregulatory paths of metabolic disease: unveil molecular mechanisms of impaired immuno-vascular response to target visceral inflammation by rewiring regulatory T cell energetic circuits

An integrated human-in vitro approach to explore the role of miRNAs in the allergic asthma

Exploring the role of SEMA6A in the formation of hypothalamic and cerebellar circuits to unravel new molecular mechanisms underlying reproductive and feeding behaviours.

PAtient Lipidome As biomarker of Cancer immunothErapy (PALACE study)

SLC15A4 (Solute Carrier 15 member A4): integrated in vitro-in vivo analysis and functional characterization

Organic cation transporters relevant to drug discovery: multifaceted approaches to unravel their structure/function relationships with the aim of identifying novel substrates and inhibitors enabling their application in therapy

The cellular function of SERINC proteins and their role in retroviral infection.

EXTRAcellular Vesicles to Unravel Heart Failure Molecular and Clinical Phenotypes (EXTRAHF)

Piano di Sostegno alla Ricerca 2015-2017 - Linea 2 "Dotazione annuale per attività istituzionali" (anno 2022)

Precision medicine in neurodegenerative diseases: feasibility study on plasma diagnostic and prognostic markers

Investigating the neuro-immune-metabolic interfaces in human and experimental atherosclerosis